Research Scientist | Duke University School of Medicine

School of Medicine Overview: Established in 1930, Duke University School of Medicine ranks sixth among medical schools nationwide. It fosters an inclusive environment with a focus on interdisciplinary collaboration and translating scientific discoveries to improve global health. The School, along with Duke University Health System, includes Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, and more.

Position Overview: A Research Scientist position is available in the Department of Neurosurgery. The role involves supporting a multidisciplinary research program in surgery, radiation oncology, medical oncology, and palliative care. Key responsibilities include:

1. Research Coordination and Development:
   • Develop and manage the program’s translational research portfolio.
   • Assist with grant writing for local, federal, and foundation grants.
   • Oversee clinically-annotated banked tissues from patient samples.
2. Research Focus:
   • Investigate genetic and epigenetic alterations in metastatic bone and spine diseases.
   • Characterize tumor-specific and tumor microenvironment changes.
   • Study pre-clinical models of novel therapeutics.

Key Responsibilities:

• Perform molecular biology and microbiology techniques (e.g., PCR, ELISA).
• Maintain and manage mouse models (e.g., husbandry, genotyping).
• Conduct animal models of disease and relevant experimental procedures.
• Execute literature reviews and guide research.
• Perform technical procedures like PCR, qPCR, and electrophoresis.
• Analyze complex genetic and morphologic data.
• Maintain organized records and manage laboratory operations.
• Aid with grant writing, IRB applications, budget preparation, and protocol submission.
• Assist with the training of residents, students, and undergraduates.

Requirements:

• PhD or equivalent in Cancer Biology, Genetics, or Cell Biology.
• Track record of publication in peer-reviewed journals.
• Experience in molecular cloning, post-translational regulation, and animal models.
• Skills in bioinformatics and molecular biology techniques preferred.
• Strong communication, organizational, and problem-solving skills.

How to Apply: Submit a single PDF file to NSU_HR@duke.edu including:

• Cover letter detailing research and career goals, with expertise in either molecular cloning or post-translational regulation.
• Curriculum vitae with a publication list and brief descriptions of contributions.
• Names and contact information for 3-5 references.